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Pharmaceutical care for a patient with acute kidney injury caused by tacrolimus combined with tenofovir after hepatitis B virus related liver transplantation

Published on Mar. 24, 2023Total Views: 717 times Total Downloads: 310 times Download Mobile

Author: Duo HAO 1 Jun-Bao LIU 1 Yun-Qiang WU 2 Yan TAN 3 Miao-Miao PENG 4

Affiliation: 1. Department of Pharmacy, Ordos Central Hospital, Ordos 017000, Inner Mongolia Autonomous Region, China 2. Department of Pharmacy, Changzhou First People’s Hospital, Changzhou 213000, Jiangsu Province, China 3. Department of Pharmacy, People’s Hospital of Xiangxi Tujia and Miao Autonomous Prefecture, Jishou 416000, Hunan Province, China 4. Department of Pharmacy, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing 210008, China

Keywords: Acute kidney injury Tacrolimus Tenofovir Clinical pharmacist Pharmaceutical care

DOI: 10.19960/j.issn.1005-0698.202303012

Reference: Duo HAO, Jun-Bao LIU, Yun-Qiang WU, Yan TAN, Miao-Miao PENG.Pharmaceutical care for a patient with acute kidney injury caused by tacrolimus combined with tenofovir after hepatitis B virus related liver transplantation[J].Yaowu Liuxingbingxue Zazhi,2023, 32(2): 343-349.DOI: 10.19960/j.issn.1005-0698.202303012.[Article in Chinese]

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Abstract

The clinical pharmacist systematically analyzed the correlation between drug-induced renal injury caused by long-term administration of tacrolimus and tenofovir dipivoxil fumarate in a patient with hepatitis B virus infection after liver transplantation. In combination with relevant guidelines and literature reports, the clinical pharmacist suggested that doctors replace the patient's medication with sirolimus and tenofovir alafenamide fumarate, and give the patient medication education and supervision. After relevant treatment, the patient's renal function gradually returned to normal, and the disease was controlled and discharged smoothly. Clinical pharmacists use their professional knowledge to provide medication advice to patients with drug-induced diseases and carry out pharmaceutical services, which will help improve the safety and effectiveness of long-term medication for patients.

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References

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