Chinese Journal of Pharmacoepidemiology

Chinese name: Yaowu Liuxingbingxue Zazhi

Responsible:Hubei Medical Products Administration

Sponsor:Hubei Institute for Drug Control
Chinese Pharmaceutical Association
Zhongnan Hospital of Wuhan University

Organization:Zhongnan Medical Journal Press of Zhongnan Hospital of Wuhan University

Information:Monthly ISSN 1005-0698 CN 42-1333/RCODEN YLZAAQ

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Influence of drug factors on falls in elderly patients with chronic diseases in the communities of Wuhan Qingshan district and research on prediction model

2023,32(9):997-1007

Objective To analyze the influence of drug factors on falls in the elderly patients with chronic diseases in the communities of Wuhan Qingshan district, and to construct a prediction model.Methods The elderly with chronic diseases in four communities of Wuhan Qingshan district were selected as the subjects by cluster random sampling method, the information on patients' age, gender, med
Effect of flos lonicerae medicated serum on the activity of LPS induced human periodontal membrane cells and the mechanism of NLRP3/IL-1β pathway

2023,32(9):1017-1025

Objective To investigate the effects of flos lonicerae containing serum on the activity of human periodontal membrane cells (HPDLCs) and NLRP3, IL-1β pathway induced by lipopolysaccharide (LPS).Methods Twenty rats were divided into controll group (normal saline) and flos lonicerae group (5.0 g·kg-1) based on a random number table method, with 10 rats in each group. HPDLCs cells were di
Analysis of a case of thrombocytopenia induced by pralsetinib

2023,32(8):956-960

In this paper, a case of a 58-year-old RET fusion of positive patient with advanced non-small cell lung cancer, who appeared grade 4 thrombocytopenia after receiving pralsetinib 400 mg qd regularly for anti-tumor therapy, was reported. Before the treatment, the patient's hemogram was normal. After continuous administration of pralsetinib for 27 days, the patient's platelet count (Plt) began to dec
Pharmaceutical caring of neutrophil deficiency and histiocytic necrotizing lymphadenitis induced by methimazole

2023,32(8):950-955

In this report, we described a case of a clinical practice, in which the pharmacist was involved in the treatment of a patient, who was diagnosed with neutrophil deficiency and histiocytic necrotizing lymphadenitis induced by methimazole. The patient was admitted to the hospital for hyperthyroidism and neutrophil deficiency. After anti-infection and antiviral treatment, the patient had poor treatm
Preparation and in vitro release of sildenafil citrate loaded nanostructured lipid carrier

2023,32(7):774-779

Objective To prepare sildenafil citrate loaded nanostructured lipid carriers (SC-NLCs), characterize their physical and chemical properties, and evaluate their in vitro release.Methods SC-NLCs were prepared by thin film ultrasonic dispersion method, and their physical and chemical properties were investigated. The content of sildenafil citrate in SC-NLCs released in vitro was determina

Chinese Journal of Pharmacoepidemiology

Chinese name: Yaowu Liuxingbingxue Zazhi

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