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Study on the prevention of sufentanil-induced cough reflex during general anesthesia induction of breast mass resection by auricular point bean embedding

Published on Apr. 27, 2025Total Views: 48 times Total Downloads: 13 times Download Mobile

Author: LUO Rui 1 LI Yao 2 WU Yongli 1 WANG Weiwei 1

Affiliation: 1. Department of Anesthesiology, Sichuan Second Hospital of Traditional Chinese Medicine, Chengdu 610000, China 2. Department of Ultrasound, Jinjiang Daguan Hospital, Chengdu 610000, China

Keywords: Auricular point bean embedding Sufentanil Breast mass resection Coughing response Prevention Generalized eneralized estimation equation

DOI: 10.12173/j.issn.1005-0698.202412087

Reference: LUO Rui, LI Yao, WU Yongli, WANG Weiwei. Study on the prevention of sufentanil-induced cough reflex during general anesthesia induction of breast mass resection by auricular point bean embedding[J]. Yaowu Liuxingbingxue Zazhi, 2025, 34(4): 391-397. DOI: 10.12173/j.issn.1005-0698.202412087.[Article in Chinese]

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Abstract

Objective  To explore the preventive effect of auricular point bean embedding on sufentanil-induced cough reflex during induction of general anesthesia undergoing breast mass resection.

Methods  Clinical data of patients undergoing elective mammary mass resection with general anesthesia from June 2021 to May 2023 were retrospectively collected. The patients who received auricular point bean embedding therapy before surgery were included in the observation group, and patients who did not receive auricular point bean embedding therapy before surgery were included in the control group. The propensity score matching (PSM) method was used to perform 1∶1 matching based on basic data. The time effect, intergroup effect and interaction effect of vital signs parameters were analyzed by repeated measures analysis of variance. The GEE was used to analyze visual analogue scale (VAS) at different time points after operation. The Log-binomial regression model was used to analyze the incidence of postoperative adverse reactions and the association between subtypes.

Results  After PSM, 50 patients were included in the observation and control groups. The time effect, intergroup effect and interaction effect of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR) and blood oxygen saturation (SpO2) in 2 groups were statistically significant (P<0.05). Within the same group, SBP, DBP, MAP, HR and SpO2 were statistically significant at immediately after intravenous sufentanil injection (T1), 2 min after injection (T2), 1 min before intubation (T3) and 1 min after intubation (T4) (P<0.05). At T2, SBP, DBP, MAP and HR in the observation group were significantly lower than those in the control group, and SpO2 was significantly higher than that in the control group (P<0.05). The cough control, VAS score and total incidence of postoperative adverse reactions in the observation group were significantly better than those in the control group (P<0.05). The result of GEE model analysis showed that the improvement of postoperative VAS scores of patients in the observation group was better than that in the control group (P<0.05).

Conclusion  Preoperative auricular point bean embedding has a specific preventive effect on sufentanil induced cough reaction in patients with breast mass resection under general anesthesia.

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References

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