Uncariae Ramulus Cum Uncis has the effects of wind-extinguishing and convulsion resolving, clearing heat and liver smoothing It can be used to treat cancer, cardio-cerebrovascular diseases, neurodegenerative diseases, depression and other diseases. Studies have shown that Uncariae Ramulus Cum Uncis has significant anti-tumor activity and has inhibitory effects on many kinds of cancers, and monoterpene indole alkaloids are the main source of pharmacological effects of Uncariae Ramulus Cum Uncis. This paper reviewed the research related to the anti-tumor effect of monoterpene indole alkaloids from Uncariae Ramulus Cum Uncis in the last decade, and the anti-tumor mechanism was summarized to offer theoretical basis for the further study of monoterpene indole alkaloids in Uncariae Ramulus Cum Uncis.

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