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基于贝叶斯核机器回归的醛类物质与高尿酸血症关联性研究
BING Shuang
HUANG Ru
ZHANG Yiying
DOI:10.12173/j.issn.1005-0698.202503175
Aldehydes
Uric acid
Hyperuricemia
Bayesian kernel machine regression
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基于 XGBoost 的他汀类药物用药者急性肝损伤预测模型的开发与验证
MENG Xianglong
YU Yuelin
SUN Yexiang
SHEN Peng
JIANG Zhiqin
ZHU Yu
YIN Yueqi
ZHAN Siyan
WANG Shengfeng
DOI:10.12173/j.issn.1005-0698.202502023
Statins
Acute liver injury
Prediction model
XGBoost algorithm
Cost-sensitive learning
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轻度认知障碍罕见逆转的认知轨迹建模
QIN Yao
HUO Yanji
ZHOU Jing
ZHOU Yan
HAN Hongjuan
CUI Jing
YU Hongmei
DOI:10.12173/j.issn.1005-0698.202503205
Mild cognitive impairment
Reversion
Rare events
Functional principal component analysis
Multi-state model
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小样本多组学数据下利用注意力和元学习进行孤独症诊断的方法研究
WANG Qi
XIE Kun
LIANG Xuezhi
LUO Xiangyang
LIU Ying
CHEN Wen
DOI:10.12173/j.issn.1005-0698.202412113
Autism diagnosis
Attention mechanism
Meta learning
Small sample
Multi-omics data integration
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罕见病临床研究数据采集与管理难点和数智化应对策略
GUO Jian
Gulidanna·Asihaer
ZHANG Shuyang
DOI:10.12173/j.issn.1005-0698.202502053
Rare disease
Data collection
Data management
Digital intelligence
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数智化时代的罕见病临床研究设计与实施策略
SUN Fengyu
CAO Borui
CHEN Nana
ZHONG Xinwen
HOU Yan
PENG Zhihang
DOI:10.12173/j.issn.1005-0698.202502099
Rare diseases
Clinical research
Digital intelligence
Artificial intelligence
Study design
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围手术期药物相关罕见不良反应发现的真实世界数据基础与方法学进展
YIN Xuan
HUANG Ruijian
KONG Siyu
ZHOU Jifang
DOI:10.12173/j.issn.1005-0698.202411007
Adverse drug reaction
Perioperative
Pharmacovigilance
Digital and intelligent integration
Real-world study
Methodology
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稀有真实世界数据驱动的目标试验模拟在药物再利用中的研究进展
LI Bosheng
HUANG Xuan
WANG Wenxuan
YANG Wenyun
YAN Fangrong
DOI:10.12173/j.issn.1005-0698.202501061
Target trial emulation
Real-world data
Propensity Score
Drug repurposing
Digital intelligence technology
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面向医学小样本数据的人工智能方法及应用研究进展
WANG Longhao
QIAN Li
WU Yazhou
DOI:10.12173/j.issn.1005-0698.202412135
Small sample data
Artificial intelligence methods
Medical applications
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大数据驱动的罕见事件非均衡数据分析方法研究进展
ZHOU Jiangjie
WANG Yutong
FENG Tian
MENG Xianglong
LIANG Baosheng
WANG Shengfeng
DOI:10.12173/j.issn.1005-0698.202411080
Rare events
Imbalanced data
Data-driven
Deep learning
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检索增强生成技术在医学人工智能中的应用与前沿探索
JIN Zhe
ZOU Jian
LI Xiao
Lyu Jiaxin
HU Zhongxu
FENG Da
DOI:10.12173/j.issn.1005-0698.202503219
Large language model
Retrieval-augmented generation
Hallucination problem
Medical information retrieval
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数智化技术在罕见病诊疗中的应用现状与展望
YANG Yujie
QI Leyuan
CAO Yanbo
WEN Xiaotian
LIU Jicong
CHEN Bixiao
LIU Yawei
HE Guohua
TIAN Yu
DOI:10.12173/j.issn.1005-0698.202503209
Rare diseases
Digital intelligence
Full life-cycle
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迁移学习在罕见病研究中的应用与展望
ZHENG Xueying
QIN Guoyou
YU Yongfu
DOI:10.12173/j.issn.1005-0698.202412136
Rare diseases
Scarce data
Transfer learning
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1例痛风石破溃继发化脓性关节炎合并脓毒血症病例的治疗与监护
MA Hongyan
XU Gengrui
HUANG Kaiyuan
WANG Xiaokang
WU Haidong
DENG Kai
XIE Peitao
DOI:10.12173/j.issn.1005-0698.202502026
Gout stones
Suppurative arthritis
Sepsis
Pharmaceutical care
Methicillin-sensitive Staphylococcus aureus
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《药物流行病学研究方法学指南(第2版)》及其系列解读(8):统计分析策略的制定与注意事项
WANG Qing
FENG Xinyan
WANG Dandan
Gu Zenan
MAO Guangyun
WANG Yi
DOI:10.12173/j.issn.1005-0698.202508028
Pharmacoepidemiology
Methodology
Guildelines
Statistical analysis strategies
Bias control
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