Against the backdrop of the construction of New Medical Sciences and the rapid advancement of artificial intelligence (AI) technologies, postgraduate education in pharmacology faces problems such as accelerated iteration of disciplinary knowledge, insufficient cultivation of scientific research thinking, and ambiguous pathways for integrating AI into core curricula. Based on teaching practice, this paper explores an artificial intelligence (AI)-integrated teaching model for postgraduate students majoring in pharmacology along three main threads: literature analysis, experimental design, and academic expression. By introducing authentic research scenarios including intelligent deduction of GLP-1 mechanisms, AI-assisted PK prediction, and simulated defense on animal ethics, an integrated training pathway linking teaching and scientific research is established. This paper puts forward corresponding countermeasures for potential challenges in practical promotion and application, and hopes to offer references for postgraduate education in pharmacology as well as the teaching reform of pharmacy-related majors.
1. 王运武,田阳,任楷文.教育数字化赋能教育强国建设的战略构想及实现路径——《教育强国建设规划纲要(2024—2035年)》解读[J].中国医学教育技术,2025,39(4):425-431.WangYW,TianY,RenKW.The strategic conception and implementation path of empowering the construction of a leading country in education with the educational digitalization——Interpretation of the Outline of the Plan for Building a Leading Country in Education (2024—2035)[J].China Medical Education Technology,2025,39(4):425-431.DOI:10.13566/j.cnki.cmet.cn61-1317/g4.202504001.
2. 谢宗志,彭秋颖,刘晓晴.人工智能赋能高等教育高质量发展的研究与实践[J].高校教育研究,2025,1(3):7-15.XieZZ,PengQY,LiuXQ.Research and practice on artificial intelligence empowering the high-quality development of higher education[J].Higher Education Research,2025,1(3):7-15.DOI:10.12479/questpress-gxjyyj.20250302.
3. RyanDK,MacleanRH,BalstonA,et al.Artificial intelligence and machine learning for clinical pharmacology[J].Br J Clin Pharmacol,2024,90(3):629-639.DOI:10.1111/bcp.15930.
4. 崔立有.人工智能背景下临床药学教育改革策略[J].药学教育,2025,41(2):48-52.CuiLY.Reform strategies for clinical pharmacy education in the context of artificial intelligence[J].Pharmaceutical Education,2025,41(2):48-52.DOI:10.16243/j.cnki.32-1352/g4.2025.02.005.
5. AmbeK.Development of a data-driven prediction model of adverse drug reactions using large-scale medical information and machine learning[J].Biol Pharm Bull,2026,49(2):213-219.DOI:10.1248/bpb.b25-00641.
6. ToniE,AyatollahiH,AbbaszadehR,et al.Machine learning techniques for predicting drug-related side effects: a scoping review[J].Pharmaceuticals.2024,17(6):795.DOI:10.3390/ph 17060795.
7. 聂晓璐,吴昀效,赵厚宇,等.《药物流行病学研究方法学指南(第2版)》系列解读(17):预测模型在药物疗效与安全性评价中的应用[J].药物流行病学杂志,2026,35(5):481-492.NieXL,WuYX,ZhaoHY,et al.Guide on Methodological Standards in Pharmacoepidemiology (2nd edition) and their series interpretation(17): application of predictive models in drug effectiveness and safety evaluation[J].Chinese Journal of Pharmacoepidemiology,2026,35(5):481-492.DOI:10.12173/j.issn.1005-0698.202605004.
8. RichardsonP,GriffinI,TuckerC,et al.Baricitinib as potential treatment for 2019-nCoV acute respiratory disease[J].Lancet,2020,395(10223):e30-e31.DOI:10.1016/S0140-6736(20)30304-4.
9. RenF,AliperA,ChenJ,et al.A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models[J].Nat Biotechnol,2025,43(1):63-75.DOI:10.1038/s41587-024-02143-0.
10. 茹菲娜,哈丽美热,于思寒,等.人工智能技术融入药学人才培养的实践探索与思考[J].药学教育,2026,42(1):9-15.RuFN,HaLMR,YuSH,et al.Practical exploration and development reflections on the integration of AI technology into pharmaceutical talent cultivation[J].Pharmaceutical Education,2026,42(1):9-15.DOI:10.3969/j.issn.1007-3531.2026.01.003.
11. AhsanZ.Integrating artificial intelligence into medical education: a narrative systematic review of current applications, challenges, and future directions[J].BMC Med Educ,2025,25(1):1187.DOI:10.1186/s12909-025-07744-0.
12. PengH,KothelnikovS,EgbertME,et al.Ligand interaction landscape of transcription factors and essential enzymes in E. coli[J].Cell,2025,188(5):1441-1455.e15.DOI:10.1016/j.cell.2025.01.003.
13. ObrezanovaO.Artificial intelligence for compound pharma-cokinetics prediction[J].Curr Opin Struct Biol,2023,79:102546.DOI:10.1016/j.sbi.2023.102546.
14. ObrezanovaO,MartinssonA,WhiteheadT,et al.Prediction of in vivo pharmacokinetic parameters and time-exposure curves in rats using machine learning from the chemical structure[J].Mol Pharm,2022,19(5):1488-1504.DOI:10.1021/acs.molpharmaceut.2c00027.
15. PreiksaitisC,RoseC.Opportunities, challenges, and future directions of generative artificial intelligence in medical education: scoping review[J].JMIR Med Educ,2023,9:e48785.DOI:10.2196/48785.
16. WangLK,PaidisettyPS,CanoAM.The next paradigm shift? ChatGPT, artificial intelligence, and medical education[J].Med Teach,2023,45(8):925.DOI:10.1080/0142159X.2023.2198663.