Vol 34,2025 No.8

 Contents

Special Issue on Rare Event Research Driven by Digital Intelligence

Date of publication: August 15, 2025

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Vol 34,2025 No.7

Editorial comments of special issue on rare event research driven by digital intelligence

WANG Shengfeng

2025,34(8):845

Editorial Note
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Mining of adverse reaction signals of amlodipine based on the FAERS database and the construction of a digital and intelligent pharmacovigilance platform

HU Yanghui QIU Ziyan ZHANG Bingsong

2025,34(8):846-854

Amlodipine Adverse drug event Signal mining FAERS database Digital intelligent platform
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Association between aldehydes and hyperuricemia based on Bayesian kernel machine regression

BING Shuang HUANG Ru ZHANG Yiying

2025,34(8):855-866

Aldehydes Uric acid Hyperuricemia Bayesian kernel machine regression
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Development and validation of an XGBoost-based prediction model for acute liver injury in statin users

MENG Xianglong YU Yuelin SUN Yexiang SHEN Peng JIANG Zhiqin ZHU Yu YIN Yueqi ZHAN Siyan WANG Shengfeng

2025,34(8):867-876

Statins Acute liver injury Prediction model XGBoost algorithm Cost-sensitive learning
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Cognitive trajectories modeling of rare reversion in mild cognitive impairment

QIN Yao HUO Yanji ZHOU Jing ZHOU Yan HAN Hongjuan CUI Jing YU Hongmei

2025,34(8):877-886

Mild cognitive impairment Reversion Rare events Functional principal component analysis Multi-state model
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Study on the method of using attention mechanism and meta-learning to diagnose autism under small sample multi-omics condition

WANG Qi XIE Kun LIANG Xuezhi LUO Xiangyang LIU Ying CHEN Wen

2025,34(8):887-896

Autism diagnosis Attention mechanism Meta learning Small sample Multi-omics data integration
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 Contents

Vol 34,2025 No.8

Special Issue on Rare Event Research Driven by Digital Intelligence

Vol 34,2025 No.7

Editorial comments of special issue on rare event research driven by digital intelligence

Mining of adverse reaction signals of amlodipine based on the FAERS database and the construction of a digital and intelligent pharmacovigilance platform

Association between aldehydes and hyperuricemia based on Bayesian kernel machine regression

Development and validation of an XGBoost-based prediction model for acute liver injury in statin users

Cognitive trajectories modeling of rare reversion in mild cognitive impairment

Study on the method of using attention mechanism and meta-learning to diagnose autism under small sample multi-omics condition

Rare disease clinical research data collection and management challenges and digital intelligence response strategies

Design and implementation strategies for rare disease clinical research in the digital intelligence era

Perioperative rare adverse reactions discovery: real-world data foundations and methodological advances

Research progress on rare real-world data-driven target trial emulation for drug repurposing

Research progress on artificial intelligence methods and applications for small sample data in medicine

Research progress on big-data-driven analysis strategies for imbalanced data of rare events

Application and frontier exploration of retrieval-augmented generation technology in medical artificial intelligence

Application status and development prospect of digital intelligence technology in the diagnosis and treatment of rare diseases

Applications and prospects of transfer learning in rare diseases research