Bacillus cereus, a gram-positive bacterium, is widely distributed in soil and food. Human infections caused by Bacillus cereus are mainly food-borne and pulmonary infections are rarely reported. A case of pulmonary abscess caused by Bacillus cereus is described in this paper. There is no standard anti-infective treatment for pulmonary abscess caused by Bacillus cereus. Clinical pharmacists gave antimicrobial treatment suggestions by under-standing the epidemiological characteristics of the bacteria, referring to relevant literature and combining with the clinical conditions of patients, so that the infection foci of patient was effectively controlled and treated, which fully embodies the clinical value of clinical pharmacists.
1.Bottone EJ. Bacillus cereus, a volatile human pathogen[J]. Clin Microbiol Rev, 2010, 23(2): 382-398. DOI: 10.1128/CMR.00073-09.
2.Dietrich R, Jessberger N, Ehling-Schulz M, et al. The food poisoning toxins of Bacillus cereus[J]. Toxins (Basel), 2021, 13(2): 98. DOI: 10.3390/toxins13020098.
3.Stenfors Arnesen LP, Fagerlund A, Granum PE. From soil to gut: Bacillus cereus and its food poisoning toxins[J]. FEMS Microbiol Rev, 2008, 32(4): 579-606. DOI: 10.1111/j.1574-6976.2008.00112.x.
4.Veysseyre F, Fourcade C, Lavigne JP, et al. Bacillus cereus infection: 57 case patients and a literature re-view[J]. Med Mal Infect, 2015, 45(11-12): 436-440. DOI: 10.1016/j.medmal.2015.09.011.
5.Ishida R, Ueda K, Kitano T, et al. Fatal community-acquired Bacillus cereus pneumonia in an immu-no-competent adult man: a case report[J]. BMC Infect Dis, 2019, 19(1): 197. DOI: 10.1186/s12879-019-3836-3.
6.Tsai AL, Hsieh YC, Chen CJ, et al. Investigation of a cluster of Bacillus cereus bacteremia in neonatal care units[J]. J Microbiol Immunol Infect, 2022, 55(3): 494-502. DOI: 10.1016/j.jmii.2021.07.008.
7.Chou YL, Cheng SN, Hsieh KH, et al. Bacillus cereus septicemia in a patient with acute lymphoblastic leukemia: a case report and review of the literature[J]. J Microbiol Immunol Infect, 2016, 49(3): 448-451. DOI: 10.1016/j.jmii.2013.06.010.
8.中华医学会呼吸病学分会感染学组. 糖尿病合并肺炎诊治路径中国专家共识 [J].中华结核和呼吸杂志, 2020, 43(8): 639-647. DOI: 10.3760/cma.j.cn311282-20200508-00335.
9.Kıvanç SA, Kıvanç M, Güllülü G. Automated ribotyping and antibiotic resistance determining of Bacil-lus spp from conjunctiva of diabetic patients[J]. Iran J Basic Med Sci, 2014, 17(2): 138-144. https://pubmed.ncbi.nlm.nih.gov/24711899/.
10.Glasset B, Herbin S, Granier SA, et al. Bacillus cereus, a serious cause of nosocomial infections: epidemi-ologic and genetic survey[J]. PLoS One, 2018, 13(5): e0194346. DOI: 10.1371/journal.pone.0194346.
11.Sankararaman S, Velayuthan S. Bacillus cereus[J]. Pediatr Rev, 2013, 34(4): 196-197. DOI: 10.1542/pir.34-4-196.
12.Torkar KG, Bedenić B. Antimicrobial susceptibility and characterization of metallo-β-lactamases, ex-tended-spectrum β-lactamases, and carbapenemases of Bacillus cereus isolates[J]. Microb Pathog, 2018, 118: 140-145. DOI: 10.1016/j.micpath.2018.03.026.
13.Liu CC, Yu PF, Yu SB, et al. Assessment and molecular characterization of Bacillus cereus isolated from edible fungi in China[J]. BMC Microbiol, 2020, 20(1): 310. DOI: 10.1186/s12866-020-01996-0.
14.戴维·吉尔伯特, 亨利·钱伯斯, 迈克尔·萨格, 主编. 范洪伟, 主译. 热病: 桑德福抗微生物治疗指南, 新译第50版[M]. 北京: 中国协和医科大学出版社, 2021: 73.
15.Uchino Y, Iriyama N, Matsumoto K, et al. A case series of Bacillus cereus septicemia in patients with hematological disease[J]. Intern Med, 2012, 51(19): 2733-2738. DOI: 10.2169/internalmedicine.51.7258.
16.Ikeda M, Yagihara Y, Tatsuno K, et al. Clinical characteristics and antimicrobial susceptibility of Bacillus cereus blood stream infections[J]. Ann Clin Microbiol Antimicrob, 2015, 15(14): 43-47. DOI: 10.1186/s12941-015-0104-2.
17.Shen K, Yang MJ, Fan YX, et al. Model-based evaluation of the clinical and microbiological efficacy of vancomycin: a prospective study of Chinese adult in-house patients[J]. Clin Infect Dis, 2018, 67(S2): S256-262. DOI: 10.1093/cid/ciy667.