Objective  To count the prescriptions for oral administration of traditional Chinese medicine in the cardiovascular department, analyze the characteristics of the use of traditional Chinese medicine prescriptions, and provide basis for the pharmacovigilance of traditional Chinese medicine.

Methods  Microsoft Excel software was used to analyze the data of oral Chinese medicine prescriptions of inpatients from 2019 to 2021 in the cardiovascular department of Dong Fang Hospital of Beijing University of Chinese Medicine, including the name and syndrome type of the inpatients, the frequency, and dosage of the use of prescription drugs, as well as the classification of the four qi, five flavors, and efficacy of commonly used Chinese medicines in the cardiovascular department. The association rules in the structured query language SQL server 2008 R2 software were used for data mining, to analyze the compatibility rules and core drugs of cardiovascular traditional Chinese medicine prescriptions, and to analyze the pharmacovigilance of cardiovascular traditional Chinese medicine.

Results Statistical analysis showed that Poria cocos, Salvia miltiorrhiza radix et rhizoma, Glycyrrhizae radix et rhizome praeparata cum melle, Codonopsis radix and Paeoniae radix rubra ranked the top 5 in the frequency of consumption. The top 30 TCMs were mainly sweet, spicy and warm; the heart and spleen are the main channels; the main effects are tonifying and promoting blood circulation and removing blood stasis. The common combinations of two drugs in cardiovascular department Glycyrrhizae radix et rhizome praeparata cum melle - Poria cocos, Citri reticulatae pericarpium- Poria cocos, Codonopsis radix - Poria cocos; Poria cocos, Salvia miltiorrhiza radix et rhizoma, Paeoniae radix rubra, Codonopsis radix, Astragall radix, Chuanxiong rhizome and Glycyrrhizae radix et rhizome praeparata cum melle are the core drugs of the prescription. These drugs are mainly used to treat cardiovascular diseases caused by qi deficiency, blood stasis and phlegm dampness. Except Codonopsis radix, the maximum dose of other Chinese herbal pieces exceeded the Pharmacopoeia limit.

Conclusion  The main symptoms of cardiovascular inpatients are Qi deficiency and blood stasis syndrome and phlegm dampness internal obstruction syndrome. The treatment is mainly based on the traditional Chinese medicine of invigorating Qi and activating blood circulation, and the core medication is mainly characterized by invigorating qi and spleen, activating blood and promoting dampness. There is a problem of overdose in commonly used prescriptions.

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