The clinical pharmacist participated in the treatment process of catheter-related bloodstream infection (CRBSI) in a patient with the antimicrobial allergy. Based on the previous drug allergy history and the actual hospital drug reserve, high dose of tigecycline (first dose 200 mg, 100 mg, q12h maintenance) combined with fosfomycin (1 g, bid) for empirical anti-CRBSI treatment was recommended with the patient's consent, and the clinician adopted this opinion. Then the infection was effectively controlled and the condition was discharged. Through consultation, clinical pharmacists assisted doctors to develop individualized treatment plans, provided precise pharmaceutical monitoring services for patients, and provided reference for the safe, effective and rational use of antibiotics for special groups such as allergic patients.

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