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Cost-utility analysis of Shenling Baizhu powder in treatment of sarcopenia in older men

Published on Apr. 27, 2023Total Views: 1348 times Total Downloads: 510 times Download Mobile

Author: Huan-Huan JIANG 1 Hui-Qin SHEN 2 Zhi-Xiu WANG 2 Yun-Fei CHEN 3 Hui GUO 2 Na XU 2

Affiliation: 1. Department of Pharmacy, Affiliated Hosipital of North China University of Science and Technology, Tangshan 063000, Hebei Province, China 2. Department of Pharmacy, the Second Affiliated Hosipital of Hebei North University, Zhangjiakou 075000, Hebei Province, China 3. Department of Clinical Nutrition, the Second Affiliated Hosipital of Hebei North University, Zhangjiakou 075000, Hebei Province, China

Keywords: Shenling Baizhu powder Sarcopenia Cost-utility analysis Pharmacoeco-nomics

DOI: 10.19960/j.issn.1005-0698.202304003

Reference: Huan-Huan JIANG, Hui-Qin SHEN, Zhi-Xiu WANG, Yun-Fei CHEN, Hui GUO, Na XU.Cost-utility analysis of Shenling Baizhu powder in treatment of sarcopenia in older men[J].Yaowu Liuxingbingxue Zazhi,2023, 32(4): 376-383.DOI: 10.19960/j.issn.1005-0698.202304003.[Article in Chinese]

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Abstract

Objective To explore the economic value of Shenling Baizhu powder in treatment of sarcopenia in older men by using cost-utility analysis.

Methods A total of 280 older men with sarcopenia were divided into a intervention group (140 cases) and a control group (140 cases). Patients in the two groups were given nutrition sports treatment, patients in the intervention group were given Shenling Baizhu powder on the basis of nutrition sports treatment, patients in both groups were followed up for 24 weeks. From the perspective of healthcare, by establishing a decision tree model and using the TreeAge Pro 2011, cost-utility analysis was performed for the two treatment schemes. The un-certainty of the results was evaluated with sensitivity analysis.

Results  Compared with the control group, the intervention group had higher cost ( 5 019.46 yuan vs. 4 864.57 yuan ) and higher utility [0.90357 quality adjusted life years (QALYs) vs. 0.89430 QALYs]. The incremental cost-utility ratio value was 16 712.05 yuan/QALY, which was lower than the willing to pay threshold. The results of sensitivity analysis were consistent with those of cost-utility analysis.

Conclusion  Compared with using the nutrition sports treatment alone, the use of Shenling Baizhu powder combined with nutrition sports treatment in elderly male sarcopenia patients is more cost-utility.

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References

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