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A case clinical analysis and pharmaceutical care of severe complications of multi-space infection in patients with head and neck tumors

Published on Sep. 28, 2023Total Views: 1339 times Total Downloads: 416 times Download Mobile

Author: Yao-Dong PING 1, 2 Xiao-Long XU 3 Bao-Min ZHENG 3 Li-Feng ZHAO 2 Ben-Ben ZHU 2

Affiliation: 1. Department of Pharmacy, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China 2. Department of Pharmacy, Peking University Cancer Hospital Inner Mongolia Hospital, Affiliated Cancer Hospital of Inner Mongolia Medical University, Hohhot 010020, China 3. Department of Radiotherapy, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China

Keywords: Head and neck tumors Multi-space infection Antibacterial drug Pharmaceutical care

DOI: 10.19960/j.issn.1005-0698.202309005

Reference: Yao-Dong PING, Xiao-Long XU, Bao-Min ZHENG, Li-Feng ZHAO, Ben-Ben ZHU.A case clinical analysis and pharmaceutical care of severe complications of multi-space infection in patients with head and neck tumors[J].Yaowu Liuxingbingxue Zazhi,2023, 32(9): 991-996.DOI: 10.19960/j.issn.1005-0698.202309005.[Article in Chinese]

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Abstract

Clinical pharmacists participated in the treatment of severe complications of oral maxillofacial and neck space infection in a patient with recurrent adenoid cystic carcinoma of the left upper jaw after systemic chemotherapy combined with targeted therapy. Clinical pharmacists analyzed the risk factors of multiple space infection and the distribution characteristics of pathogenic bacteria by referring to literature data, and determined protocols for imipenem cilastatin plus clindamycin in the acute phase and moxifloxacin plus fosfomycin in the stable phase, and the clinician adopted this opinion. Then the infection was effectively controlled and the condition was discharged. Through consultation, clinical pharmacists assisted doctors to develop individualized treatment plans, provided reference for the safe, effective and rational use of antibiotics.

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References

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